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PMEPA1 Gene Isoforms: A Potential Biomarker and Therapeutic Target in Prostate Cancer.
Sharad S, Dobi A, Srivastava S, Srinivasan A, Li H. Sharad S, et al. Biomolecules. 2020 Aug 22;10(9):1221. doi: 10.3390/biom10091221. Biomolecules. 2020. PMID: 32842649 Free PMC article. Review.
It was soon followed by the documentation of the expression and functional analysis of transmembrane prostate androgen-induced protein (TMEPAI)/PMEPA1 in other solid tumors including renal, colon, breast, lung, and ovarian cancers. ...PMEPA1 serves as an esse …
It was soon followed by the documentation of the expression and functional analysis of transmembrane prostate androgen-induced protein (TMEP …
EGF- and cell-cycle-regulated STAG1/PMEPA1/ERG1.2 belongs to a conserved gene family and is overexpressed and amplified in breast and ovarian cancer.
Giannini G, Ambrosini MI, Di Marcotullio L, Cerignoli F, Zani M, MacKay AR, Screpanti I, Frati L, Gulino A. Giannini G, et al. Mol Carcinog. 2003 Dec;38(4):188-200. doi: 10.1002/mc.10162. Mol Carcinog. 2003. PMID: 14639658
Finally, we have demonstrated that, besides prostate cancer and renal cell carcinoma, STAG1 was also overexpressed in breast and ovarian cancer cell lines and in breast primary tumors. Although in most cases STAG1 overexpression is probably due to the abnormal activation o …
Finally, we have demonstrated that, besides prostate cancer and renal cell carcinoma, STAG1 was also overexpressed in breast and ovarian …
Mutation or loss of p53 differentially modifies TGFbeta action in ovarian cancer.
Ó hAinmhire E, Quartuccio SM, Cheng W, Ahmed RA, King SM, Burdette JE. Ó hAinmhire E, et al. PLoS One. 2014 Feb 20;9(2):e89553. doi: 10.1371/journal.pone.0089553. eCollection 2014. PLoS One. 2014. PMID: 24586866 Free PMC article.
Ovarian cancer is the most lethal gynecological disease affecting women in the US. ...Only ovarian cancer cells expressing wild-type p53 were growth inhibited by TGFbeta, while ovarian cancer cells that were mutant or null p53 were not. ...
Ovarian cancer is the most lethal gynecological disease affecting women in the US. ...Only ovarian cancer cells expressing wil …